Biochem/physiol Actions

Cell permeable: no

Reversible: no

Target IC₅₀: 300 µM against trypsin-like serine proteases, papain and some cysteine proteases

Product does not compete with ATP.

Primary TargetTrypsin-like serine proteases

General description

Effective concentration: 1-100 µM.

Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca²⁺-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain, and some cysteine proteases (IC₅₀ ~500 ng/ml). Effective at concentrations of 1-100 µM.

Peptidyl arginine aldehyde protease inhibitor produced by actinomycetes. Inhibitor of Ca²⁺-dependent endopeptidases. Has specificity similar to Leupeptin (Cat. No. 108975). Inhibits trypsin-like serine proteases, papain and some cysteine proteases (IC₅₀ = 300 µM).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Lyupina, Y.V., et al. 1996. Eur. J. Pharmacol. 304, 23.Umezawa, H. 1976. Methods Enzymol.55, 678.

Packaging

5 mg in Glass bottle

10 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 month at -20°C.

Warning

Toxicity: Standard Handling (A)